Code Repository

Roberts-Christini Model

Roberts-Christini Model

The Roberts-Christini model is a mathematical guinea pig ventricular myocyte model developed to study ischemia and reperfusion in cardiac cells. Myocardial ischemia, commonly observed when arteries supplying the heart become occluded, results when...

“NHE Inhibition Does Not Improve Na+ or Ca2+Overload During Reperfusion: Using Modeling to Illuminate the Mechanisms Underlying a Therapeutic Failure,” PLoS Comput Biol, 7(10): e1002241 (2011).